京都大学医学部附属病院 探索医療センター検証部  Div. Clinical Trial Design & Management, Translational Research Center, Kyoto University Hospital
3rd US-Japan Biostatistics Workshop
- Preliminary Agenda -

 
October 7, 2005
Inamori Hall, Faculty of Medicine, Kyoto University


 

OPENING REMARKS
9:00 a.m.
Masanori Fukushima, M.D., Ph.D.,
Kyoto University & Translational Research Informatics Center

CLINICAL TRIALS
9:10 a.m. Inter-Patient Variability and Misspecification of Dose-Response Modeling in CRM
Naoki Ishizuka, Ph.D.,
International Medical Center of Japan
9:30 a.m. Bayesian Sequential Analysis in Translational Research
Satoshi Teramukai, Ph.D.,
Kyoto University & Translational Research Informatics Center
9:50 a.m. The Mean Squared Error D-Optimum Design for Selection of Sampling Times in Pharmacokinetics
Takashi Daimon, Ph.D.,
University of Shizuoka
10:10 a.m. Break
10:20 a.m. Designs for Trials of Personalized Therapy Based on Chemosensitivity
Seiichiro Yamamoto, Ph.D.,
National Cancer Center
10:40 a.m. Designs for Trials of Targeted Therapy in Oncology
John Crowley, Ph.D.,
Cancer Research And Biostatistics
11:00 a.m. Analysis of Neurotoxicity of Taxane
Yasuo Ohashi, Ph.D.,
University of Tokyo
11:20 a.m. Break

OBSERVATIONAL ANALYSIS & CAUSAL INFERENCE
11:30 a.m. Comparison of Efficiency among Estimation Methods in Case-Control Studies within Cohort
Sachiko Tanaka, Ph.D. and Seiichiro Yamamoto, Ph.D.,
National Cancer Center
11:50 a.m. Randomized-Based Analysis of All Eligible Patients Adaptive to Protocol Amendment of Eligibility Criteria
Kenichi Yoshimura, Ph.D.,
National Cancer Center
12:10 p.m. A Sensitivity Analysis for Unmeasured Confounding on the Estimation of Causal Effect
Yasutaka Chiba, Ph.D., Yutaka Matsuyama, Ph.D., and Tosiya Sato, Ph.D.,
Kyoto University
12:30 p.m. Lunch

KEYNOTE LECTURE: COMPUTATIONAL BIOLOGY
2:00 p.m. An Overview of the Bioconductor Project and Applications in Computational Biology
Robert Gentleman, Ph.D.,
Fred Hutchinson Cancer Research Center
2:40 p.m. Break

GENE EXPRESSION PROFILING
3:00 p.m. Use of High Throughput Genomics in a Large Single Institution Trial to Predict Survival of Patients with Myeloma
John Shaughnessy, Ph.D.
Myeloma Institute for Research and Therapy, University of Arkansas for Medical Sciences
3:20 p.m. Comparison of Prognostic Prediction Methods using Subsets of Significant Genes
Takeharu Yamanaka, Ph.D.,
Translational Research Informatics Center
3:40 p.m. Sample Size Calculations for Selecting Differentially Expressed Genes Based on Gene Ranking
Shigeyuki Matsui, Ph.D.,
Kyoto University & Translational Research Informatics Center
4:00 p.m. Break

PROGNOSTIC FACTORS AND BIOMARKERS
4:10 p.m. Prognostic Modeling using Stage-wise Methods
Michael LeBlanc, Ph.D.,
Fred Hutchinson Cancer Research Center
4:30 p.m. Operating Characteristics of Prostate-Specific Antigen: Results from the Prostate Cancer Prevention Trial
Donna Pauler Ankerst, Ph.D.,
Sylvia Lawry Center for MS Research

CLOSING REMARKS
4:50 p.m.
John Crowley, Ph.D.,
Cancer Research And Biostatistics